Antipsychotics and Lipid Levels in a Veteran Population

Risk of lipid abnormality with haloperidol, olanzapine, quetiapine, and risperidone in a Veterans Affairs population. 09/17/09. Second-generation antipsychotics can cause lipid elevations at a greater rate than older typical antipsychotics. This risk may not be equivalent amongst the second-generation antipsychotics. We conducted a computerized, retrospective, nonrandomized, case-control analysis of 6331 patients receiving antipsychotics. In conclusion, treatment with risperidone or haloperidol was associated with a more favorable lipid profile than with olanzapine or quetiapine.  International Clinical Psychopharmacology via PubMed